drugset / Trial / NCT02408146

The Effect of Parecoxib Sodium Intravenous Patient-controlled Analgesia in Laparotomic Liver Resection

NCT02408146

RandomizedParallel-groupDouble-blindTreatment

Summary

The investigators hypothesized that using new intravenous infusion pump of patient-controlled analgesia (parecoxib sodium 1 mg/mL + normal saline) would significantly improve postoperative pain control compare to conventional intravenous infusion pump of patient-controlled analgesia (fentanyl citrate 20 mg/mL/kg + ondansetron hydrochloride 16 mg/8 mL + normal saline). This prospective randomized controlled trial was designed to evaluate the benefit of new intravenous infusion pump of patient-controlled analgesia (parecoxib sodium 1 mg/mL + normal saline) for postoperative analgesia after laparotomic liver resection.

Timeline

Start
2014-01
Primary completion
2015-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Fentanyl Other / unclassified 20 unknown Intravenous
Subject Parecoxib Small molecule 1 mg/ml Intravenous
Subject Parecoxib Small molecule 40 mg Intravenous
Background Celecoxib Other / unclassified Oral
Background Ondansetron Other / unclassified 16 mg Intravenous

Indications