Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children

Phase 4 Completed 200 enrolled Attikon Hospital

RandomizedParallel-groupSingle-blindScreening

Summary

The aim of this prospective randomized study is to investigate comparatively the effect of neostigmine-atropine versus sugammadex on speed and quality of recovery and on postoperative cognitive function \& behavior in children undergoing ENT surgery under general anaesthesia.

Timeline

Start: 2015-06
Primary completion: 2018-03
Completion: 2018-04

Publications

Background Glinka L, Onichimowski D, Sieniuta P, Korecki A. [Sugammadex--two years in clinical practice]. Anestezjol Intens Ter. 2010 Jul-Sep;42(3):155-9. Polish.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Atropine	Other / unclassified	0.02 mg/kg	Intravenous
Comparator	Neostigmine	Other / unclassified	0.05 mg/kg	Intravenous
Comparator	Sugammadex	Other / unclassified	2 mg/kg	Intravenous

Indications

No indication recorded.