drugset / Trial / NCT02500225
Comparison the Effects of Etomidate and Sevoflurane During Electroconvulsive Therapy
RandomizedCrossoverTriple-blindTreatment
Summary
The purpose of the study was to investigate the effects of etomidate or sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure, hemodynamic response and recovery profiles.
Timeline
- Start
- 2017-01
- Primary completion
- 2017-02
- Completion
- 2017-02
Publications
- Results Janouschek H, Nickl-Jockschat T, Haeck M, Gillmann B, Grozinger M. Comparison of methohexital and etomidate as anesthetic agents for electroconvulsive therapy in affective and psychotic disorders. J Psychiatr Res. 2013 May;47(5):686-93. doi: 10.1016/j.jpsychires.2012.12.019. Epub 2013 Feb 9.
- Results Toprak HI, Gedik E, Begec Z, Ozturk E, Kaya B, Ersoy MO. Sevoflurane as an alternative anaesthetic for electroconvulsive therapy. J ECT. 2005 Jun;21(2):108-10. doi: 10.1097/01.yct.0000166633.73555.28.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Etomidate | Small molecule | 0.2 mg/kg | — |
| Comparator | Sevoflurane | Other / unclassified | 8 % | Inhaled |
Indications
No indication recorded.