drugset / Trial / NCT02513147
HIV Reservoir Dynamics After Switching to Dolutegravir in Patients on a PI and 2 NRTI Based Regimen
Phase 4
Completed
44 enrolled
Hospital Universitari Vall d'Hebron Research Institute
IrsiCaixa · collabUniversity Hospital, Ghent · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to assess changes in viral reservoir after changing IP/r to dolutegravir in HIV-1 infected patients maintaining undetectable viral load on Antiretroviral Therapy (ART).
Timeline
- Start
- 2015-06
- Primary completion
- 2016-11
- Completion
- 2016-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atazanavir | Other / unclassified | 400 mg | — |
| Subject | Darunavir | Small molecule | — | — |
| Subject | Dolutegravir | Other / unclassified | 50 mg | — |
| Subject | Fosamprenavir | Small molecule | — | — |
| Subject | Lopinavir | Other / unclassified | — | — |
| Background | Ritonavir | Other / unclassified | 100 mg | — |
Indications
No indication recorded.