drugset / Trial / NCT02520479
"Sandwich" Chemotherapy With Radiotherapy in Newly Diagnosed, Stage IE to IIE, ENKTL
NaSingle-groupOpen-labelTreatment
Summary
A phase 2 study was conducted of "sandwich" protocols, with earlier RT after an initial 2 of P-CHOP (Pegaspargase, cyclophosphamide,vincristine, doxorubicin and dexamethasone ), followed by further two "consolidation" cycles,to explore the appropriate mode of combined modality therapy (CMT) in early stage ENKTL.
Timeline
- Start
- 2013-06
- Primary completion
- 2017-12
- Completion
- 2018-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 10 mg | — |
| Subject | Doxorubicin | Other / unclassified | 50 mg/m2 | — |
| Subject | P-CHOP | Unknown | 750 mg/m2 | — |
| Subject | Pegaspargase | Protein / enzyme biologic | 2500 iu | — |
| Subject | Vincristine | Small molecule | 1.4 mg/m2 | — |
Indications
No indication recorded.