drugset / Trial / NCT02524743
The Prevention of Pain Associated With Rocuronium Injection
RandomizedCrossoverDouble-blindTreatment
Summary
The purpose of this study is to determine whether efficacy of different doses of lidocain and acetaminophen for the prevention of rocuronium injection pain and frequency of withdrawal movements during the general anesthesia induction period.
Timeline
- Start
- 2014-05
- Primary completion
- 2014-09
- Completion
- 2014-10
Publications
- Background Steegers MA, Robertson EN. Pain on injection of rocuronium bromide. Anesth Analg. 1996 Jul;83(1):203. doi: 10.1097/00000539-199607000-00065. No abstract available.
- Background Kwak HJ, Kim JY, Kim YB, Min SK, Moon BK, Kim JY. Pharmacological prevention of rocuronium-induced injection pain or withdrawal movements: a meta-analysis. J Anesth. 2013 Oct;27(5):742-9. doi: 10.1007/s00540-013-1595-7. Epub 2013 Mar 22.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | 25 mg | Intravenous |
| Comparator | Acetaminophen | Small molecule | 50 mg | Intravenous |
| Comparator | Lidocaine | Other / unclassified | 20 mg | Intravenous |
| Comparator | Lidocaine | Other / unclassified | 40 mg | Intravenous |
Indications
No indication recorded.