drugset / Trial / NCT02548936
Efficacy and Safety of Simvastatin-ezetimibe Combination Therapy Among Patients With SLE
RandomizedParallel-groupSingle-blindPrevention
Summary
This is a randomized single-blind trial. This study aimed to determine if intensive lipid-lowering therapy (simvastatin-ezetimibe combination therapy) could reduce the progression of atherosclerosis effectively and safely among SLE patients with carotid artery intima thickening. The study results were expected to be helpful for SLE patients in preventing atherosclerosis.
Timeline
- Start
- 2015-04
- Primary completion
- 2016-10
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ezetimibe | Unknown | 20 mg | Oral |
| Subject | Simvastatin | Small molecule | 10 mg | Oral |