A Drug-drug Interaction Study Between Daclatasvir and Metformin

Summary

This study aims to provide clinical information on a potential drug-drug interaction between daclatasvir and metformin.

Timeline

Start

2016-01

Primary completion

2016-03

Completion

2016-04

Publications

• Results Smolders EJ, Colbers A, de Kanter CTMM, Velthoven-Graafland K, Wolberink LT, van Ewijk-Beneken Kolmer N, Drenth JPH, Aarnoutse RE, Tack CJ, Burger DM. Metformin and daclatasvir: absence of a pharmacokinetic-pharmacodynamic drug interaction in healthy volunteers. Br J Clin Pharmacol. 2017 Oct;83(10):2225-2234. doi: 10.1111/bcp.13323. Epub 2017 Jun 6.

Drugs

Indications