Adjuvant Chemotherapy Based on the Adenosine Triphosphate Tumor Chemosensitivity Assay for Hepatocellular Carcinoma After Liver Transplantation

Phase 2 Withdrawn Zhejiang University

RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a randomized, open-label, controlled study that will explore the efficacy of individualized adjuvant chemotherapy based on the adenosine triphosphate tumor chemosensitivity assay for patients with hepatocellular carcinoma after liver transplantation.

Timeline

Start: 2017-11-01
Primary completion: 2018-11
Completion: 2018-12

Outcome

Outcome not reported

Stopped (Enrollment): “no patients enrolled”

Publications

Background Lin HS, Wan RH, Gao LH, Li JF, Shan RF, Shi J. Adjuvant chemotherapy after liver transplantation for hepatocellular carcinoma: a systematic review and a meta-analysis. Hepatobiliary Pancreat Dis Int. 2015 Jun;14(3):236-45. doi: 10.1016/s1499-3872(15)60373-3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cisplatin	Other / unclassified	—	—
Subject	Docetaxel	Small molecule	—	—
Subject	Doxorubicin	Other / unclassified	—	—
Subject	Gemcitabine	Small molecule	—	—
Subject	Irinotecan	Small molecule	—	—
Subject	Oxaliplatin	Small molecule	85 mg/m2	—
Subject	Paclitaxel	Small molecule	—	—
Subject	fluorouracil	Small molecule	2800 mg/m2	—