drugset / Trial / NCT02651636

Combined Therapy With Myo-inositol and Alpha-Lipoic Acid in PCOS Women

NCT02651636

NaSingle-groupOpen-labelTreatment

Summary

The aim of our study is to investigate the effects of a combined treatment of alpha-lipoic acid and myoinositol on clinical, endocrine and metabolic features of women affected by PCOS. The study Group included 40 patients treated with a combined therapy of alpha-lipoic acid (800 mg), myoinositol (2000 mg) and folic acid (400 mcg) daily for six months. The investigation includes menstrual pattern, hirsutism score, hormonal assays, oral glucose tolerance test, lipidic profile at baseline and after six months of treatment.

Timeline

Start
2014-06
Primary completion
2015-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Inositol Small molecule 2000 mg
Subject alpha-lipoic acid Small molecule 800 mg
Subject folic acid Other / unclassified 400 ug