Drugs / Inositol
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Inositol

Small molecule

Developed for
polycystic ovary syndrome · female infertility · retinopathy of prematurity · bipolar disorder · bronchopulmonary dysplasia · glucose intolerance · anxiety · autism
+14 more · colon carcinoma · colon dysplasia · infertility disorder · menstrual disorder · mood disorder · neural tube defect · non-small cell lung carcinoma · non-verbal learning disability · ovarian dysfunction · pregnancy disorder · rectal carcinoma · hypertrichosis · obesity disorder · trichotillomania
Investigated by
Beni-Suef University · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · NICHD Neonatal Research Network · National Eye Institute (NEI) · American University of Beirut Medical Center · Massachusetts General Hospital
+33 more · National Cancer Institute (NCI) · National Center for Research Resources (NCRR) · Near East University, Turkey · AGUNCO Obstetrics and Gynecology Centre · AZ Jan Palfijn Gent · Biosearch S.A. · Catholic University of the Sacred Heart · Daewoong Pharmaceutical Co. LTD. · Demarest Lloyd Jr. Foundation · Eman Basuni Ebrahim Mowad · Fatima Tariq · Gedeon Richter Plc. · Institute of Child Health · Islamabad Medical and Dental College · Jarrow Formulas Inc · Khyber Medical University Peshawar · Milton S. Hershey Medical Center · Mst.Sumyara Khatun · Muhammad Aamir Latif · National Center for Complementary and Integrative Health (NCCIH) · National Institute of Mental Health (NIMH) · Nishtar Medical University · Our Lady of Lourdes Hospital Waregem · PAEC general hospital · Quaid-e-Azam Medical College · Rashid Latif Medical College · Ronald M. Glick, MD · The Fine Foundation · University Hospital Brussels · University Hospital, Antwerp · University Hospital, Ghent · University of Cagliari · University of Sao Paulo General Hospital

Trials 36 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT04204044 Nov 2020 → May 2021 polycystic ovary syndrome Rashid Latif Medical College Unknown No outcome recorded
Phase 12 trials
Phase 1 NCT07459595 May → Jul 2026 overdue polycystic ovary syndrome Fatima Tariq Not yet recruiting No outcome recorded
Phase 1 NCT00452829 Sep 2009 → Jun 2013 neural tube defect Institute of Child Health Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT02811133 Aug → Oct 2023 anxiety, bipolar disorder Ronald M. Glick, MD Withdrawn No outcome recorded
Phase 1/2 NCT01111292 Oct 2010 → Sep 2014 colon carcinoma, colon dysplasia, rectal carcinoma National Cancer Institute (NCI) Terminated No outcome recorded
Phase 25 trials
Phase 2 NCT07635082 Feb 2024 → Jun 2025 polycystic ovary syndrome Eman Basuni Ebrahim Mowad Completed No outcome recorded
Phase 2 NCT03864068 Jan 2020 → Dec 2025 anovulation, glucose intolerance, polycystic ovary syndrome Milton S. Hershey Medical Center Completed No outcome recorded
Phase 2 NCT01030575 Jan 2010 → May 2011 bronchopulmonary dysplasia, fetal growth restriction, retinopathy of prematurity NICHD Neonatal Research Network Completed No outcome recorded
Phase 2 NCT00783705 Nov 2008 → May 2014 non-small cell lung carcinoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00349726 Jun 2006 → Dec 2007 bronchopulmonary dysplasia, fetal growth restriction, retinopathy of prematurity NICHD Neonatal Research Network Completed No outcome recorded
Phase 2/33 trials
Phase 2/3 NCT05900661 Jul → Sep 2023 Beni-Suef University Unknown No outcome recorded
Phase 2/3 NCT04273256 Feb 2020 → Feb 2022 ovarian dysfunction American University of Beirut Medical Center Unknown No outcome recorded
Phase 2/3 NCT03201601 Feb 2016 → May 2017 infertility disorder, polycystic ovary syndrome Biosearch S.A. Completed No outcome recorded
Phase 35 trials
Phase 3 NCT07323589 Jan → Jul 2025 polycystic ovary syndrome PAEC general hospital Completed No outcome recorded
Phase 3 NCT06405243 Jun → Dec 2024 polycystic ovary syndrome Beni-Suef University Unknown No outcome recorded
Phase 3 NCT06405204 Jun → Dec 2024 Beni-Suef University Unknown No outcome recorded
Phase 3 NCT03767569 Sep 2018 → Apr 2020 female infertility, polycystic ovary syndrome University Hospital Brussels Unknown No outcome recorded
Phase 3 NCT01954082 Apr 2014 → Dec 2016 retinopathy of prematurity NICHD Neonatal Research Network Terminated No outcome recorded
Phase 47 trials
Phase 4 NCT07701525 Jun → Nov 2025 polycystic ovary syndrome Nishtar Medical University Completed No outcome recorded
Phase 4 NCT04306692 Jul 2020 → Apr 2021 female infertility, polycystic ovary syndrome University Hospital, Ghent Terminated No outcome recorded
Phase 4 NCT03911414 Jun 2019 → Dec 2024 mood disorder Massachusetts General Hospital Completed No outcome recorded
Phase 4 NCT03757585 May 2019 → May 2024 autism, non-verbal learning disability Massachusetts General Hospital Completed No outcome recorded
Phase 4 NCT03177122 Mar 2017 → Dec 2023 female infertility American University of Beirut Medical Center Unknown No outcome recorded
Phase 4 NCT02418130 Oct 2014 → Mar 2015 Daewoong Pharmaceutical Co. LTD. Completed No outcome recorded
Phase 4 NCT01511822 polycystic ovary syndrome AGUNCO Obstetrics and Gynecology Centre Completed No outcome recorded
Phase not applicable11 trials
NCT07629895 Sep 2026 → Apr 2027 expected polycystic ovary syndrome Quaid-e-Azam Medical College Not yet recruiting No outcome recorded
NCT07604779 May → Dec 2026 expected polycystic ovary syndrome Beni-Suef University Active not recruiting No outcome recorded
NCT07266259 Sep 2025 → Aug 2026 overdue polycystic ovary syndrome Mst.Sumyara Khatun Recruiting No outcome recorded
NCT07380841 May → Nov 2025 metabolic syndrome X, polycystic ovary syndrome Islamabad Medical and Dental College Completed No outcome recorded
NCT07387679 Nov 2024 → May 2025 polycystic ovary syndrome Muhammad Aamir Latif Completed No outcome recorded
NCT05767515 Jul 2023 → Feb 2024 female infertility, polycystic ovary syndrome Khyber Medical University Peshawar Completed No outcome recorded
NCT05951309 Sep 2021 → Sep 2022 polycystic ovary syndrome Near East University, Turkey Completed No outcome recorded
NCT05943158 Jun 2021 → Jun 2022 pregnancy disorder Near East University, Turkey Completed No outcome recorded
NCT04892186 Mar 2021 → Oct 2023 glucose intolerance, polycystic ovary syndrome University of Sao Paulo General Hospital Completed No outcome recorded
NCT02651636 Jun 2014 → Jul 2015 menstrual disorder, polycystic ovary syndrome Catholic University of the Sacred Heart Completed No outcome recorded
Also used as a comparator or background therapy in 14 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT01574261 Comparator Mar → Aug 2012 polycystic ovary syndrome Catholic University of the Sacred Heart Unknown No outcome recorded
Phase 11 trial
Phase 1 NCT06170463 Comparator Aug 2022 → Mar 2023 polycystic ovary syndrome Zagazig University Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03153436 Comparator Aug 2016 → Apr 2017 Sohag University Completed No outcome recorded
Phase 23 trials
Phase 2 NCT04867252 Comparator May → Aug 2021 polycystic ovary syndrome Khyber Medical University Peshawar Completed No outcome recorded
Phase 2 NCT02633462 Comparator May 2015 → Oct 2016 periodontitis, polycystic ovary syndrome Postgraduate Institute of Dental Sciences Rohtak Unknown No outcome recorded
Phase 2 NCT01875445 Comparator May 2013 → May 2016 trichotillomania University of Chicago Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT07585396 Comparator May 2025 → May 2026 infertility disorder, polycystic ovary syndrome Kafrelsheikh University Completed No outcome recorded
Phase 31 trial
Phase 3 NCT07630779 Background Mar → Sep 2026 expected polycystic ovary syndrome Beni-Suef University Recruiting No outcome recorded
Phase 42 trials
Phase 4 NCT03283813 Comparator Feb 2018 → Dec 2023 disorder of zinc metabolism, obesity disorder Azienda Ospedaliero Universitaria Maggiore della Carita Completed No outcome recorded
Phase 4 NCT01396486 Comparator Feb 2012 → Apr 2019 bipolar disorder Massachusetts General Hospital Completed No outcome recorded
Phase not applicable4 trials
NCT07058675 Comparator Nov 2024 → May 2025 polycystic ovary syndrome Benha University Completed No outcome recorded
NCT01555190 Comparator Jan 2012 → Dec 2013 hypertrichosis, menstrual disorder, polycystic ovary syndrome Catholic University of the Sacred Heart Completed No outcome recorded
NCT01791647 Comparator Jun 2011 → Dec 2012 polycystic ovary syndrome Catholic University of the Sacred Heart Completed No outcome recorded
NCT02397291 Comparator Jan 2001 → Dec 2016 fetal growth restriction University of Colorado, Denver Terminated No outcome recorded

Evidence & citations 13 cited values

Every value below carries the sentence it was read from. 51 sources stand behind the page.

FieldValueCited text
Known as Inositol ClinicalTrials.gov intervention name — accepted as the source's own label NCT01030575
12

NCT03864068

NCT00012558

NCT01396486

NCT03757585

NCT01111292

NCT02811133

NCT00783705

NCT00452829

NCT01875445

NCT03911414

NCT01574261

NCT02418130

Known as Cyclohexanehexol ChEMBL registry synonym — accepted as the source's own label CHEMBL1222251
Known as I-inositol ChEMBL registry synonym — accepted as the source's own label CHEMBL1222251
Known as Inositol, myo ChEMBL registry synonym — accepted as the source's own label CHEMBL1222251
Known as Meso-inositol ChEMBL registry synonym — accepted as the source's own label CHEMBL1222251
Known as MYO myoinositol/d-chiro-inositol combination (MYO/DCI) in 40:1 ratiotwice daily” NCT07058675
Known as Myo-inositol “This group is given myoinositol+d-chiro inositol+folic acid once a day (inofolic combi, ITF company, Italy) (myoinositol 550 miligram+ d-chiroinositol 13,8 miligram+folic acid...” NCT05951309
38

Myo-inositol (MI) is one of the most important of the 9 inositol stereoisomers, and this molecule has been studied many times in the literature in recent years.” NCT05943158

“Participants allocated to this arm will receive myo-inositol 2 g orally twice daily for a duration of 3 months prior to ovulation induction.” NCT07635082

“The promising role of two of its isomers namely Myo-inositol (MI) and D-chiro-inositol (DCI) in the treatment of PCOS has been documented.” NCT05767515

“The objective of this study is to compare the outcome of Metformin versus Myo-inositol in the management of polycystic ovarian disease.” NCT07459595

Myo-Inositol is a carbocyclic sugar, belongs to Inositol group and is an important component of structural lipids.” NCT04867252

Myo-inositol (MI) protects against MAFLD through reduction of hepatic accumulation of triglycerides.” NCT06170463

“60 mg/kg (1.2ml/kg) of myo-inositol 5% given intravenously over 20 minutes.” NCT00349726

“Levocarnitine 330 mg and Myoinositol 750 mg twice daily for 3 months” NCT07266259

NCT07323589

NCT04273256

NCT07604779

NCT06405243

NCT03201601

NCT02397291

NCT03767569

NCT03177122

NCT03153436

NCT02651636

NCT01555190

NCT02633462

NCT01954082

NCT07585396

NCT07387679

NCT04306692

NCT07459595

NCT01511822

NCT04204044

NCT07701525

NCT07058675

NCT03283813

NCT06405204

NCT05900661

NCT07630779

NCT07380841

NCT04892186

NCT01791647

NCT07629895

NCT05943158

Known as NSC-25142 ChEMBL registry synonym — accepted as the source's own label CHEMBL1222251
Known as NSC-404118 ChEMBL registry synonym — accepted as the source's own label CHEMBL1222251
Known as NSC-55551 ChEMBL registry synonym — accepted as the source's own label CHEMBL1222251
Known as NSC-8101 ChEMBL registry synonym — accepted as the source's own label CHEMBL1222251
Modality Other / unclassified “Inositol, a dietary supplement” NCT03864068
Route Intravenous “given intravenously over 20 minutes.” NCT00349726