drugset / Trial / NCT06170463

Insulin Sensitizers Role in Control of PCOS Vicious Cycle.

NCT06170463

Phase 1 Completed 210 enrolled Zagazig University
RandomizedParallel-groupOpen-labelTreatment

Summary

PCOS is a common and complex disease affecting women of reproductive age. It is characterized by its complex pathological symptoms and mechanisms resulting in endocrine and metabolic dysfunction. PCOS is highly associated with various metabolic and endocrinal disorders. Metformin is mainly used for its glucose-lowering effects for treatment and prevention of type-2 diabetes mellitus (DM), gestational DM, and PCOS. Myo-inositol (MI) protects against MAFLD through reduction of hepatic accumulation of triglycerides.

Timeline

Start
2022-08-01
Primary completion
2023-03-01
Completion
2023-04-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator DCI Unknown
Comparator Inositol Small molecule
Comparator Metformin Small molecule 500 mg