drugset / Trial / NCT06170463
Insulin Sensitizers Role in Control of PCOS Vicious Cycle.
RandomizedParallel-groupOpen-labelTreatment
Summary
PCOS is a common and complex disease affecting women of reproductive age. It is characterized by its complex pathological symptoms and mechanisms resulting in endocrine and metabolic dysfunction. PCOS is highly associated with various metabolic and endocrinal disorders. Metformin is mainly used for its glucose-lowering effects for treatment and prevention of type-2 diabetes mellitus (DM), gestational DM, and PCOS. Myo-inositol (MI) protects against MAFLD through reduction of hepatic accumulation of triglycerides.
Timeline
- Start
- 2022-08-01
- Primary completion
- 2023-03-01
- Completion
- 2023-04-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | DCI | Unknown | — | — |
| Comparator | Inositol | Small molecule | — | — |
| Comparator | Metformin | Small molecule | 500 mg | — |