drugset / Trial / NCT07459595

Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study

NCT07459595

Phase 1 Not yet recruiting 60 enrolled Fatima Tariq
RandomizedParallel-groupSingle-blindTreatment

Summary

In polycystic ovary syndrome (PCOS), changes in physical appearance i.e. weight gain, hirsutism, menstrual disturbances and infertility result in reduced quality-of-life. PCOS is one of the most common endocrine disorders affecting about 4% to 8% of women of reproductive age. Diagnosis is primarily clinical with Rotterdam criteria being the most commonly followed criteria, which require the presence of two out of the three criteria including oligo and/or anovulation, clinical and/or biochemical signs of hyperandrogenism and polycystic ovaries on ultrasound. The objective of this study is to compare the outcome of Metformin versus Myo-inositol in the management of polycystic ovarian disease.

Timeline

Start
2026-05-01
Primary completion
2026-07-31
Completion
2026-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Inositol Small molecule 1 g Oral
Comparator Metformin Small molecule 850 mg Oral