The Effect of Adding Nalbuphine to Intrathecal Morphine on Analgesic Efficacy and Side Effects After Cesarean Section

Phase 2 Completed 80 enrolled Abdelrady S Ibrahim, MD

RandomizedParallel-groupDouble-blindPrevention

Summary

The primary endpoint of this study is to investigate the effect of adding nalbuphine to intrathecal morphine on quality of postoperative analgesia and Morphine related side effects post- cesarean delivery.

Timeline

Start: 2016-07
Primary completion: 2017-10
Completion: 2017-10

Publications

Background Culebras X, Gaggero G, Zatloukal J, Kern C, Marti RA. Advantages of intrathecal nalbuphine, compared with intrathecal morphine, after cesarean delivery: an evaluation of postoperative analgesia and adverse effects. Anesth Analg. 2000 Sep;91(3):601-5. doi: 10.1097/00000539-200009000-00019.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Morphine	Other / unclassified	0.2 mg	Intrathecal
Comparator	Morphine	Other / unclassified	0.5 mg	Intrathecal
Comparator	Nalbuphine	Small molecule	0.2 mg	—
Comparator	Bupivacaine	Other / unclassified	10 mg	Intrathecal

Indications

No indication recorded.