drugset / Trial / NCT02724111

Effect of Neuromuscular Blockade on Operating Conditions and Overall Satisfaction During Spinal Surgery

NCT02724111 ↗

RandomizedParallel-groupTriple-blindSupportive care

Summary

The investigators aim to investigate operating conditions, postoperative recovery and overall satisfaction of surgeons between deep neuromuscular blockade (NMB) group and restricted NMB group during spinal surgery under general anesthesia. The investigators hypothesize that this study can present good surgical conditions, postoperative recovery outcomes and overall satisfaction of surgeons in deep NMB group, thereby proving the advantages of deep NMB as well as flaws of restricted NMB in spine surgeries.

Timeline

Start
2016-05-15
Primary completion
2017-02-16
Completion
2017-02-16

Outcome

Met primary endpoint

registry analysis (superiority test); Deep Neuromuscular Blockade vs Restricted Neuromuscular Blockade; p <0.001; t-test, 2 sided NCT02724111 ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject Rocuronium Other / unclassified 5 mg —
Comparator Sugammadex Other / unclassified 2 mg/kg —
Comparator Sugammadex Other / unclassified 4 mg/kg —