drugset / Trial / NCT02725060
Autoimmune Basis for Postural Tachycardia Syndrome
Enrolling by invitation
58 enrolled
Vanderbilt University Medical Center
University of Oklahoma · collab
NaSingle-groupOpen-labelOther
Summary
The purpose of this study is to see if some people with postural tachycardia syndrome (POTS) have higher levels of immune proteins (autoantibodies) directed against receptors of the autonomic nervous system, and if these autoantibodies make a difference in their POTS symptoms. The investigators also want to see if the levels of these autoantibodies stay the same over time.
Timeline
- Start
- 2016-02
- Primary completion
- 2026-10
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Isoproterenol | Small molecule | 0.025 ug | Intravenous |
| Subject | Phenylephrine | Small molecule | 12.5 ug | Intravenous |
| Subject | Phenylephrine | Small molecule | 800 ug | Intravenous |