The Effects of Metformin on Glycemic Control and Insulin Sensitivity in Adolescents With T1DM

Summary

The investigators intends to carry out a randomized, cross-over, prospective study which will last 48 weeks in youth with T1DM followed up by the center. The purpose is to observe the effects of metformin on glycemic control and insulin sensitivity in adolescents with T1DM based on insulin therapy by using 72h CGMS and hyperinsulinemic euglycemic clamps.

Timeline

Start

2016-06

Primary completion

2018-01

Completion

2018-01

Drugs

Indications