drugset / Trial / NCT02785003
Ketamine in Colorectal Surgery
RandomizedParallel-groupTriple-blindTreatment
Summary
This study will evaluate the effectiveness of ketamine infusions in the management of acute pain following open or laparoscopic colorectal surgery cases. Half of patients will receive the institutional standard of care and a placebo infusion (no active medication). The other half of patients will receive the institutional standard of care and a ketamine infusion. All subjects and staff will be blinded as to whether they are receiving placebo or ketamine.
Timeline
- Start
- 2016-07
- Primary completion
- 2017-08
- Completion
- 2018-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 2 ug/kg | Intravenous |
| Background | Acetaminophen | Small molecule | 650 mg | Oral |
| Background | Acetaminophen | Small molecule | 1000 mg | Oral |
| Background | Alvimopan | Small molecule | — | — |
| Background | Hydromorphone | Other / unclassified | — | — |
| Background | Morphine | Other / unclassified | — | — |