drugset / Trial / NCT02819908
Dropless™ vs. Less Drops™ Pharmaceutical Regimens After Cataract Surgery
RandomizedParallel-groupOpen-labelTreatment
Summary
To compare the relative effectiveness of the Imprimis Dropless™ (TriMoxiVanc) intraocular solution with the Less Drops™ topical formulation of PredMoxiKeterolac (given for the first week post op) followed by PredKeterolac (given for weeks 2 to 4 after surgery). The hypothesis is that the "dropless" regimen will be non-inferior to the "less drops" regimen in terms of post-operative IOP changes, post-operative healing, and visual quality.
Timeline
- Start
- 2015-09
- Primary completion
- 2016-04
- Completion
- 2016-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketorolac Tromethamine | Small molecule | — | Topical |
| Comparator | Moxifloxacin | Small molecule | — | Intravitreal |
| Comparator | Moxifloxacin | Small molecule | — | Topical |
| Comparator | Prednisolone | Other / unclassified | — | Topical |
| Comparator | Triamcinolone Acetonide | Other / unclassified | — | Intravitreal |
| Comparator | Vancomycin | Other / unclassified | — | Intravitreal |