drugset / Trial / NCT02825147
Pegaspargase and Methotrexate Based Regimens for Newly Diagnosed Extranodal NK/T Cell Lymphoma
NaSingle-groupOpen-labelTreatment
Summary
Extranodal NK/T cell lymphoma is an aggressive tumor with higher incidence in Asia.Traditional CHOP/CHOP-like regiment can't produce satisfied outcome for the patients. Asparaginase-based treatment has been demonstrated as promising response rate and survival superiority. Stage-specified regimen may bring out exciting efficacy with good safety.
Timeline
- Start
- 2013-09
- Primary completion
- 2016-03
- Completion
- 2017-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methotrexate | Small molecule | 1000 mg/m2 | — |
| Subject | Pegaspargase | Protein / enzyme biologic | 2500 unknown | — |
| Background | Dexamethasone | Small molecule | 40 mg | — |
| Background | Etoposide | Small molecule | 100 mg | — |