drugset / Trial / NCT02837614
Evaluation of Preoperative Submucosal Dexamethasone in Third Molar Surgery
RandomizedParallel-groupOpen-labelTreatment
Summary
The study composed of sixty patients, each of whom required surgical extraction of a single impacted mandibular third molar under local anaesthesia. The patients were randomly allocated to one of 3 groups of 20 each. The three groups were categorized as Group A (intramuscular dexamethasone), Group B (submucosal dexamethasone) and Group C (control). The objective measurements of facial pain, swelling, and trismus was performed by an independent examiner at baseline (preoperatively), and at days 1, 3, and 7 postoperatively.
Timeline
- Start
- 2015-10
- Primary completion
- 2016-01
- Completion
- 2016-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexamethasone | Small molecule | 4 mg | Intramuscular |
| Background | Acetaminophen | Small molecule | 500 mg | — |
| Background | Amoxicillin | Other / unclassified | 500 mg | Oral |