drugset / Trial / NCT02866136
Conservative Treatments of Retinoblastoma
Non-randomizedParallel-groupOpen-labelTreatment
Summary
Conservative treatments of retinoblastoma (RETINO 2011) 1. -Multicentric non randomised, phase II study for the patients treated by chemoreduction (VP16, carboplatin) followed by chemothermotherapy without laser treatment at day 8 2. -Multicentric non randomised, phase II study for the patients with bilateral very asymmetric dis-ease (Group D eye on one of the eye) or unilateral presentation groups B/C/D according to the age and vitreous seeding 3. \- Multicentric non randomised, phase II study for the patients treated by 6 cycles of three drugs regimen and local treatments for bilateral group D eyes or on the only eye.
Timeline
- Start
- 2012-02
- Primary completion
- 2023-01
- Completion
- 2035-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carboplatin | Small molecule | — | — |
| Subject | Etoposide | Small molecule | — | — |
| Subject | Melphalan | Small molecule | — | Other |
| Subject | Vincristine | Small molecule | — | — |