drugset / Trial / NCT02870283
Cost- Effectiveness and Quality of Life Assessment in Mood Disorder
RandomizedCrossoverOpen-labelTreatment
Summary
To evaluate the effectiveness of three systematic interventions for Bipolar Disorder (BD) mixed episodes using medications available in the Brazilian Public Healthcare System (SUS), and assessment of the quality of life of these patients. A randomized pragmatic trial was conducted. An algorithm was developed for the treatment of episodes of bipolar mixed episodes.
Timeline
- Start
- 2010-05
- Primary completion
- 2014-11
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Carbamazepine | Small molecule | 600 mg | — |
| Comparator | Carbamazepine | Small molecule | 1200 mg | — |
| Comparator | Lithium | Unknown | 900 mg | — |
| Comparator | Lithium | Unknown | 1500 mg | — |
| Comparator | Valproic Acid | Small molecule | 1000 mg | — |
| Comparator | Valproic Acid | Small molecule | 1500 mg | — |