drugset / Trial / NCT02870283

Cost- Effectiveness and Quality of Life Assessment in Mood Disorder

NCT02870283

Phase 4 Completed 107 enrolled Federal University of Rio Grande do Sul
RandomizedCrossoverOpen-labelTreatment

Summary

To evaluate the effectiveness of three systematic interventions for Bipolar Disorder (BD) mixed episodes using medications available in the Brazilian Public Healthcare System (SUS), and assessment of the quality of life of these patients. A randomized pragmatic trial was conducted. An algorithm was developed for the treatment of episodes of bipolar mixed episodes.

Timeline

Start
2010-05
Primary completion
2014-11
Completion
2015-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Carbamazepine Small molecule 600 mg
Comparator Carbamazepine Small molecule 1200 mg
Comparator Lithium Unknown 900 mg
Comparator Lithium Unknown 1500 mg
Comparator Valproic Acid Small molecule 1000 mg
Comparator Valproic Acid Small molecule 1500 mg

Indications