Transverse Abdominis Plane Block for Anterior Approach Spine Surgery

Phase 2 Completed 43 enrolled Rennes University Hospital

RandomizedParallel-groupTriple-blindTreatment

Summary

Therapeutic, prospective, randomized, double blind, placebo-controlled, in intention to treat, monocentric study to evaluate the analgesic efficacy of a bilateral TAP block after spine surgery with 24 hours morphine consumption

Timeline

Start: 2016-11-07
Primary completion: 2019-05-25
Completion: 2019-05-25

Publications

Results Coquet A, Sion A, Bourgoin A, Ropars M, Beloeil H. Transversus abdominis plane block for anterior lumbar interbody fusion: a randomized controlled trial. Spine J. 2023 Aug;23(8):1137-1143. doi: 10.1016/j.spinee.2023.03.013. Epub 2023 Apr 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ropivacaine	Other / unclassified	75 mg	Other
Background	Cisatracurium	Small molecule	2 mg/ml	—
Background	Dexamethasone	Small molecule	8 mg	—
Background	Ketamine	Small molecule	0.15 mg/kg	—
Background	Propofol	Small molecule	10 mg/ml	—
Background	Remifentanil	Small molecule	50 ug/ml	—

Transverse Abdominis Plane Block for Anterior Approach Spine Surgery

Summary

Timeline

Publications

Drugs

Indications