drugset / Trial / NCT02909751
Tocotrienol in Combination With Neoadjuvant Chemotherapy for Women With Breast Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to investigate whether tocotrienol can improve the effect and reduce the side effects of standard chemotherapy before operation for breast cancer.
Timeline
- Start
- 2016-09-14
- Primary completion
- 2019-01-21
- Completion
- 2019-01-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tocotrienol | Small molecule | 300 mg | — |
| Background | Cyclophosphamide | Other / unclassified | 600 mg/m2 | Intravenous |
| Background | Docetaxel | Small molecule | 100 mg/m2 | Intravenous |
| Background | Epirubicin | Small molecule | 90 mg/m2 | Intravenous |
| Background | Paclitaxel | Small molecule | 80 mg/m2 | Intravenous |
| Background | Pertuzumab | Monoclonal antibody | 420 mg | Intravenous |
| Background | Trastuzumab | Monoclonal antibody | 6 mg/kg | Intravenous |