drugset / Trial / NCT02970539

Ph1b Study of Oraxol in Comb. w. Ramucirumab in Patients w. Gastric, Gastro-esophageal, or Esophageal Cancers

NCT02970539

Phase 1 Unknown 36 enrolled Athenex, Inc.
NaSequentialOpen-labelTreatment

Summary

This is a nonrandomized, open-label, single group assignment, safety, tolerability and pharmacokinetic (PK) study to determine the MTD and optimal dosing regimen of Oraxol in combination with ramucirumab.

Timeline

Start
2016-12-08
Primary completion
2019-03-27
Completion
2022-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject HM30181AK Unknown Oral
Subject Paclitaxel Small molecule Oral
Background Ramucirumab Monoclonal antibody Intravenous