drugset / Trial / NCT02995330

Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer

NCT02995330

NaSingle-groupOpen-labelTreatment

Summary

Men with progressive metastatic Castration-Resistant Prostate Cancer post first-line treatment with either androgen deprivation therapy alone or androgen deprivation therapy plus docetaxel who have an identified related female donor (mother sister, daughter, second degree relative such as granddaughter or niece) will undergo bone marrow transplantation followed by post-transplant Cytoxan (PT/Cy) and testosterone.

Timeline

Start
2017-02-09
Primary completion
2021-06-16
Completion
2021-06-16

Drugs

EvaluationDrugModalityDoseRoute
Background Cyclophosphamide Other / unclassified 50 mg/kg Intravenous
Background Testosterone Cypionate Small molecule 400 mg Intramuscular

Indications