drugset / Trial / NCT03024580
A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer
Phase 2
Unknown
20 enrolled
Brazilian National Cancer Institute
Cancer Research UK Cambridge Institute · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This pilot trial evaluates in vivo megestrol acetate (MA) modulation of steroidal receptors in advanced breast cancer.
Timeline
- Start
- 2017-03-06
- Primary completion
- 2020-03
- Completion
- 2020-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Anastrozole | Other / unclassified | 1 mg | Oral |
| Comparator | Exemestane | Small molecule | 25 mg | Oral |
| Comparator | Fulvestrant | Small molecule | 500 mg | Intramuscular |
| Comparator | Letrozole | Other / unclassified | 2.5 mg | Oral |
| Subject | Megestrol Acetate | Other / unclassified | 160 mg | Oral |
| Comparator | Tamoxifen | Small molecule | 20 mg | Oral |