drugset / Trial / NCT03068260

Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Caesarean Section.

NCT03068260

Phase 4 Completed 72 enrolled Zealand University Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

ECS is a very common procedure. A 1-year retrospective survey revealed a vast opioid consumption among the new mothers of approximately (mean±SD) 35±25 mg of oral morphine in the first 24 postoperative hours despite a multimodal analgesic regimen. The adverse effects of morphine are well known and include postoperative nausea and vomiting (PONV), itching, fatigue, constipation, confusion, respiratory depression and delayed mobilization. These adverse effects are unsound for the new mothers as well as the breast-fed, newborn children. This study aims to evaluate the efficacy of bilateral Transmuscular Quadratus Lumborum (TQL) block in reducing postoperative morphine consumption and pain.

Timeline

Start
2017-03-15
Primary completion
2017-12-01
Completion
2017-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ropivacaine Other / unclassified 0.375 % Other
Comparator Ropivacaine Other / unclassified 30 ml Other
Comparator Acetaminophen Small molecule 1 g Oral
Comparator Celecoxib Other / unclassified 100 mg Oral
Comparator Ibuprofen Small molecule 400 mg Oral
Comparator Morphine Other / unclassified 5 mg Intravenous

Indications

No indication recorded.