drugset / Trial / NCT03074773

The Effect of Paravertebral Block With Dexamethasone on Intraoperative and Postoperative Analgesia in Children Undergoing Surgery for Coarctation of Aorta

NCT03074773

Phase 1 Completed 50 enrolled Cairo University
RandomizedFactorialOpen-labelHealth-services research

Summary

Anesthetic management for surgery of aortic coarctation needs special care due to severe pain during lateral thoracotomy incision, the intraoperative hemodynamic instability related to skin incision at lateral thoracotomy, clamping and declamping of the aorta, needs of large doses of analgesia perioperative, needs of vasodilators. Also, postoperative care of the patients after repair is very important issue. The investigators will compare the effect of para-vertebral block with bupivacaine alone or with dexamethasone on Intra and postoperative analgesia.

Timeline

Start
2016-10-30
Primary completion
2017-03-30
Completion
2017-04-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 0.1 mg/kg
Comparator Bupivacaine Other / unclassified 0.5 mg/kg Other

Indications