drugset / Trial / NCT03098875
Heart Rate Variability Under Propofol and Sevoflurane
RandomizedParallel-groupDouble-blindBasic science
Summary
Patients were randomized into 2 groups according to the anesthetic, propofol or sevoflurane. Induction and maintenance were standardized, and after the end of surgery, two steady-state recordings were performed at BIS 25 and BIS 55. Bispectral Index and ECG were continuously recorded and cardiac autonomic nervous activity was investigated using spectral analysis of RR Interval variability
Timeline
- Start
- 2009-01
- Primary completion
- 2009-12
- Completion
- 2010-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | — | — |
| Comparator | Sevoflurane | Other / unclassified | — | — |
| Comparator | Remifentanil | Small molecule | — | — |
Indications
No indication recorded.