drugset / Trial / NCT03141671
Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)
RandomizedParallel-groupOpen-labelTreatment
Summary
This research study is comparing two different combinations of androgen deprivation therapy (ADT) used together with radiation as a treatment for rising PSA after radical prostatectomy (prostate cancer).
Timeline
- Start
- 2017-11-24
- Primary completion
- 2025-04-05
- Completion
- 2025-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Abiraterone acetate | Small molecule | — | Oral |
| Subject | Apalutamide | Small molecule | — | Oral |
| Subject | Bicalutamide | Other / unclassified | — | Oral |
| Background | Prednisone | Other / unclassified | — | Oral |