drugset / Trial / NCT03152955

Postoperative Analgesia in Patients With Microvascular Decompression

NCT03152955

Phase 4 Unknown 90 enrolled Xiangya Hospital of Central South University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Perioperative pain is caused by a variety of harmful factors through multiple mechanisms, therefore, reasonable postoperative analgesia should be combined with drugs or measures of different mechanism , which is called multimodal analgesia. Multimodal analgesia could minimize side effects and achieve a better analgesic effect. Commonly used strategies of multimodal analgesia are oral analgesic drug, nerve block, patient controlled analgesia and so on. This study will observe the effect of multimodal analgesia on postoperative pain in patients with microvascular decompression and record side effects. Finally, it will provide technical support for the guidance of postoperative analgesia in patients of trigeminal neuralgia.

Timeline

Start
2017-05-15
Primary completion
2018-05-15
Completion
2018-05-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule
Background Ondansetron Other / unclassified 13 ug/kg
Background Sufentanil Other / unclassified 0.02 ug/kg

Indications