drugset / Trial / NCT03189329

The Effect of Retrobulbar Block for Eye Surgery on Brain Oxygenation and Cognitive Functions in Elderly Patients

NCT03189329

Phase 4 Completed 66 enrolled Cengiz KAYA Ondokuz Mayıs University · collab
RandomizedParallel-groupSingle-blindSupportive care

Summary

The investigators measured changes in cerebral oxygen saturation (rSO2) and MMSE scores after retrobulbar block performed with levobupivacaine and lidocaine in patients undergoing vitreoretinal surgery.A total of 66 patients over the age of 60 undergoing vitreoretinal surgery with a total duration of less than 1 hour were included in this prospective, double-blinded study. The patients were randomly divided into two groups: group L (5ml, 2% lidocaine) and group LB (5ml, 0.5% levobupivacaine). Bilateral rSO2 measurements were recorded before the retrobulbar block and at 1-5 minutes post-block, during the procedure, and at 10-40 minutes post-op. MMSE was performed preoperatively and postoperatively in order to evaluate short term cognitive function. Sensory and motor block durations, pain, akinesia and conjunctival feeling scores, patient-surgeon satisfaction, and complications were also recorded.

Timeline

Start
2015-01
Primary completion
2016-01
Completion
2016-01

Publications

Drugs

EvaluationDrugModalityDoseRoute
Comparator Levobupivacaine Other / unclassified 0.5 % Other
Comparator Levobupivacaine Other / unclassified 5 ml Other
Comparator Lidocaine Other / unclassified 2 % Other
Comparator Lidocaine Other / unclassified 5 ml Other

Indications