drugset / Trial / NCT03204760

Steroids In The Management Of Acute Asthma Exacerbations In Children, Which Form Is More Suitable?

NCT03204760

Phase 2 Unknown 50 enrolled Assiut University
RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this study is to compare the efficacy of a single dose of intramuscular dexamethasone versus 3 days of twice-daily oral prednisolone in the management of mild to moderate asthma exacerbations in children and test whether this single dose of intramuscular dexamethasone 0.6 mg/kg (max. 18 mg) is equal to prednisolone 1 mg/kg/day (max. 40 mg) in the treatment of exacerbations of asthma in children, as measured by the Pediatric Respiratory Assessment Measure (PRAM).

Timeline

Start
2017-01-01
Primary completion
2017-04-30
Completion
2018-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 0.6 mg/kg Intramuscular
Subject Prednisolone Other / unclassified 1 mg/kg Oral

Indications