drugset / Trial / NCT03204760
Steroids In The Management Of Acute Asthma Exacerbations In Children, Which Form Is More Suitable?
RandomizedParallel-groupOpen-labelTreatment
Summary
The aim of this study is to compare the efficacy of a single dose of intramuscular dexamethasone versus 3 days of twice-daily oral prednisolone in the management of mild to moderate asthma exacerbations in children and test whether this single dose of intramuscular dexamethasone 0.6 mg/kg (max. 18 mg) is equal to prednisolone 1 mg/kg/day (max. 40 mg) in the treatment of exacerbations of asthma in children, as measured by the Pediatric Respiratory Assessment Measure (PRAM).
Timeline
- Start
- 2017-01-01
- Primary completion
- 2017-04-30
- Completion
- 2018-02-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 0.6 mg/kg | Intramuscular |
| Subject | Prednisolone | Other / unclassified | 1 mg/kg | Oral |