drugset / Trial / NCT03228628
Nitrous Oxide for Lumbar Puncture
Phase 4
Unknown
162 enrolled
University Hospital, Clermont-Ferrand
Hospices Civils de Lyon · collabInstitut National de la Santé Et de la Recherche Médicale, France · collabUniversity Hospital, Bordeaux · collabUniversité d'Auvergne · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
Lumbar puncture (LP) is a frequent exam that can cause pain and anxiety. In a pilot single-center study, it has been shown that nitrous oxide use during the procedure was able to reduce both pain and anxiety (Moisset et al., Eur J Neurol 2017). The goal of this multi-center trial is to confirm these results in a larger and more heterogeneous group of patients having a LP.
Timeline
- Start
- 2017-10-01
- Primary completion
- 2018-06-06
- Completion
- 2019-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nitrous Oxide | Other / unclassified | 50 % | Inhaled |
| Background | Oxygen | Other / unclassified | 50 % | Inhaled |