drugset / Trial / NCT03230474
a Small Dose of Naloxone,Minimize Intrathecal Morphine Side Effects
RandomizedParallel-groupDouble-blindTreatment
Summary
I.V naloxone decreases incidence and severity of the common morphine side effects (pruritis, nausea/emesis, constipation, urinary retention, respiratory depression and undesirable sedation) so using it as additive to intrathecal morphine in patients undergoing anal surgeries under spinal anesthesia may be beneficail
Timeline
- Start
- 2016-05
- Primary completion
- 2017-02
- Completion
- 2017-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Naloxone | Small molecule | 5 ng | — |
| Background | Bupivacaine | Other / unclassified | 5 mg | — |
| Comparator | Morphine | Other / unclassified | 0.2 mg | Intrathecal |
Indications
No indication recorded.