drugset / Trial / NCT03282045

Efficacy and Safety of the Lysobact Complete Spray®, Tantum Verde® and Pharyngal® Oromucosal Spray in the Treatment of Acute Sore Throat

NCT03282045

Phase 3 Completed 346 enrolled Bosnalijek D.D MonitorCRO · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

The primary objective of this multicenter, single-blind, randomized, placebo-controlled, prospective, comparative study with parallel design and 4-arms is to evaluate superiority of Lysobact Complete Spray® against placebo and non inferiority of Lysobact Complete Spray® against active comparators (Tantum Verde® and Pharyngal®) in terms of efficacy based on the pain VAS scores evaluated by the patient using Sore Throat Pain Intensity Scale (STPIS).

Timeline

Start
2016-10
Primary completion
2018-05-24
Completion
2018-05-24

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine Small molecule 0.28 mg Other
Comparator Lidocaine Other / unclassified 0.07 mg Other
Comparator Lidocaine Other / unclassified 0.1 mg Other
Subject Lysozyme Unknown 4 mg Other
Comparator Tantum Verde® Spray Unknown Other
Subject cetylpyridine Unknown 0.3 mg Other

Indications