drugset / Trial / NCT03283046

Study of Lenalidomide/Dexamethasone With Nivolumab and Ipilimumab in Patients With Newly Diagnosed Multiple Myeloma

NCT03283046 ↗

NaSingle-groupOpen-labelTreatment

Summary

This study has 2 parts: a Dose Escalation Part and a Dose Expansion Part. The goal of the Dose Escalation Part of this clinical research study is to find the highest tolerable dose of nivolumab in combination with ipilimumab and the standard of care (lenalidomide and dexamethasone) that can be given to patients with multiple myeloma (MM). The goal of the Dose Expansion Part of this clinical research study is to continue to study the safety of the highest tolerable dose found in Phase 1 of the study.

Timeline

Start
2017-10
Primary completion
2020-10
Completion
2020-10

Outcome

Outcome not reported

Stopped: “Similar to another study.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 40 mg Oral
Subject Ipilimumab Monoclonal antibody 3 mg/kg Intravenous
Subject Lenalidomide Other / unclassified 10 mg Oral
Subject Nivolumab Monoclonal antibody 240 mg Intravenous

Indications