drugset / Trial / NCT03318835

Thalidomide Combined With R-CHOP in Newly Diagnosed,Untreated Double-expressor Diffuse Large B-Cell Lymphoma Patients

NCT03318835

Phase 3 Unknown 162 enrolled Fudan University
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy of Thalidomide combined with R-CHOP(RT-CHOP) in newly diagnosed,untreated double-expressor Diffuse Large B-Cell Lymphoma patients (DLBCL)

Timeline

Start
2017-08-22
Primary completion
2020-08-22
Completion
2020-08-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Thalidomide Other / unclassified 200 mg Oral
Comparator Cyclophosphamide Other / unclassified 750 mg/m2 Intravenous
Comparator Doxorubicin Other / unclassified 50 mg/m2 Intravenous
Comparator Prednisone Other / unclassified 100 mg/m2 Oral
Comparator Rituximab Monoclonal antibody 375 mg/m2 Intravenous
Comparator Vincristine Small molecule 1.4 mg/m2 Intravenous

Indications

No indication recorded.