drugset / Trial / NCT03325803
Efficacy in Ablative Fractional Laser Assisted Photodynamic Therapy According to Ablative Depth for Actinic Keratosis
RandomizedFactorialTriple-blindTreatment
Summary
Er:YAG ablative fractional laser-assisted photodynamic therapy (AFL-PDT) has shown significant benefit for the treatment of actinic keratosis(AK). Er:YAG ablative fractional laser ablates the epidermis and dermis without significant thermal injury, creating microscopic ablation zones (MAZ) in the portion of the skin that the laser is applied to. The formed MAZ depends on the laser parameters such as laser depth, laser density and laser passes, which affect the treatment outcome.
Timeline
- Start
- 2015-09-01
- Primary completion
- 2016-09-30
- Completion
- 2017-09-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | methyl aminolevulinate | Small molecule | — | Topical |
| Background | Lidocaine | Other / unclassified | — | Topical |
| Background | prilocaine | Small molecule | — | Topical |