drugset / Trial / NCT03325803

Efficacy in Ablative Fractional Laser Assisted Photodynamic Therapy According to Ablative Depth for Actinic Keratosis

NCT03325803

Phase 1 Completed 45 enrolled Dong-A University
RandomizedFactorialTriple-blindTreatment

Summary

Er:YAG ablative fractional laser-assisted photodynamic therapy (AFL-PDT) has shown significant benefit for the treatment of actinic keratosis(AK). Er:YAG ablative fractional laser ablates the epidermis and dermis without significant thermal injury, creating microscopic ablation zones (MAZ) in the portion of the skin that the laser is applied to. The formed MAZ depends on the laser parameters such as laser depth, laser density and laser passes, which affect the treatment outcome.

Timeline

Start
2015-09-01
Primary completion
2016-09-30
Completion
2017-09-20

Drugs

EvaluationDrugModalityDoseRoute
Subject methyl aminolevulinate Small molecule Topical
Background Lidocaine Other / unclassified Topical
Background prilocaine Small molecule Topical

Indications