drugset / Trial / NCT03328312
Combined Use of Low-dose Sugammadex Plus Neostigmine Administered for Reversal of Rocuronium
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Reversal of rocuronium-induced neuromuscular block by the combination of low-doses of neostigmine plus sugammadex decreases the cost of anesthetic medications, while maintaining efficacy of reversal in obese patients.
Timeline
- Start
- 2017-12-01
- Primary completion
- 2018-03-01
- Completion
- 2018-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Neostigmine | Other / unclassified | 0.025 mg/kg | — |
| Comparator | Neostigmine | Other / unclassified | 0.05 mg/kg | — |
| Comparator | Sugammadex | Other / unclassified | 1 mg/kg | — |
| Comparator | Sugammadex | Other / unclassified | 2 mg/kg | — |
| Comparator | Atropine | Other / unclassified | 0.5 mg | — |
| Comparator | Atropine | Other / unclassified | 1 mg | — |