drugset / Trial / NCT03358888

Prolonged Multimodal Analgesia for Post-Discharge Pain Control After Primary Total Hip Arthroplasty

NCT03358888

Completed 228 enrolled Rothman Institute Orthopaedics
RandomizedParallel-groupSingle-blindPrevention

Summary

This is a prospective, three-arm, comparative study with a provider-crossover design. The first arm will comprise the standard of care pain regimen after discharge, which comprises PRN oxycodone, tramadol, and acetaminophen. The second arm will comprise a multimodal pain regimen; however, patients will still be routinely provided PRN oxycodone and tramadol to use on an as needed basis. The third arm will comprise a multimodal pain management protocol, which does not routinely allow for opioid consumption. However, patients will be provided a one week supply of oxycodone and tramadol for emergency pain relief only.

Timeline

Start
2017-06-05
Primary completion
2018-01-22
Completion
2018-02-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetaminophen Small molecule
Comparator Oxycodone Other / unclassified
Comparator Tramadol Other / unclassified

Indications