drugset / Trial / NCT03391414

Effects of Inhaled Bicarbonate on Airway pH in Cystic Fibrosis

NCT03391414

RandomizedCrossoverOpen-labelBasic science

Summary

This study will compare the use of inhaled concentrated sodium chloride solution to an inhaled solution of sodium bicarbonate in an attempt to decrease the thickness and stickiness of the mucus in the lungs of a person with cystic fibrosis. Also, this study is also looking at whether or not it is possible to decrease the acidity of the airways by inhaling sodium bicarbonate through nebulizer treatments.

Timeline

Start
2014-08
Primary completion
2016-07
Completion
2016-07

Drugs

EvaluationDrugModalityDoseRoute
Subject sodium bicarbonate Diagnostic / imaging agent 8.4 % Other
Comparator sodium chloride Unknown 7 % Other

Indications