drugset

drugset / Trial / NCT03411330

Safety and Efficacy of Addition of Hyaluronidase to Lidocaine and Bupivacaine in Scalp Nerves Block in Elective Craniotomy Operations, Comparative Study

NCT03411330 ↗

Phase 0 Completed 64 enrolled Cairo University Badawy Mohammed Al-Kholy · collab Hatem Abdellatif Mohamed · collab Mohamed Mahmoud Mohamed · collab Mohamed, Ahmed A., M.D. · collab Tarek Ahmed Radwan · collab

RandomizedParallel-groupDouble-blindSupportive care

Summary

Safety and efficacy of addition of hyaluronidase to lidocaine and bupivacaine in scalp nerves block in elective craniotomy operations,Comparative study

Timeline

Start: 2017-01-24
Primary completion: 2018-04-22
Completion: 2018-04-24

Publications

Mohamed AA, Radwan TA, Mohamed MM, Mohamed HA, Mohamed Elemady MF, Osman SH, Safan TF, Khair TM, Ali NA, Fahmy RS, Belita MI, Abdalla SR, Seleem AA, Atta EM, Zaid OI, Ragab AS, Salem AE, AlKholy BM. Safety and efficacy of addition of hyaluronidase to a mixture of lidocaine and bupivacaine in scalp nerves block in elective craniotomy operations; comparative study. BMC Anesthesiol. 2018 Sep 15;18(1):129. doi: 10.1186/s12871-018-0590-9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	rHuPH20	Protein / enzyme biologic	1500 iu	Other
Comparator	Bupivacaine	Other / unclassified	175 mg	Other
Comparator	Lidocaine	Other / unclassified	300 mg	Other

Indications

No indication recorded.