drugset / Trial / NCT03424356

Effects of Low Dose Neuromuscular Blocker Usage on Laryngeal Mask Application

NCT03424356

Unknown 96 enrolled TC Erciyes University
RandomizedCrossoverDouble-blindScreening

Summary

Cystoscopy is a simple, effective and reliable method in current urological practice. Anesthesia may be required in cystoscopy for therapeutic purpose, however it may not be necessary for diagnostic cystoscopy. General anesthesia, spinal anesthesia, epidural anaesthesia and senile block methods may be performed in therapeutic cystoscopy. Pain is main reason of failed cystoscopy. Sedo-analgesia and LMA are generally used for diagnostic cystoscopies. LMA is mostly placed under general anesthesia with the combination of propofol-fentanyl and volatile anesthetics. There is no need for muscle relaxant administration in LMA placement, as it is necessary for intubation. However if muscle relaxant is not used, side effects like hiccup, straining, cough, undesirable muscle movement, hypoxia and laryngeal spasm may be observed. For the improvement of the patient comfort the use of effective muscle relaxants are described in several studies in literature. This study aimed to reveal the quality of anesthesia, hemodynamics, surgical comfort, extra propofol need and recovery time while low dose of muscle relaxant rocuronium was added to propofol-fentanyl combination for LMA placement.

Timeline

Start
2017-01-04
Primary completion
2018-12-04
Completion
2018-12-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Rocuronium Other / unclassified 0.15 mg/kg
Background Fentanyl Other / unclassified 1 ug/kg
Background Propofol Small molecule 2 mg/kg
Background Propofol Small molecule 3 mg/kg

Indications

No indication recorded.