drugset / Trial / NCT03445611

Parabens Flocculation on the Anti Inflammatory Effects of Corticosteroid Injections for Total Knee Arthroplasty

NCT03445611

Phase 0 Withdrawn Loma Linda University
RandomizedParallel-groupOpen-labelPrevention

Summary

The purpose of this study is to identify whether corticosteroid use with anesthetics containing preservatives (parabens) reduces clinical effectiveness of the anti-inflammatory agent Up to 100 patients, both male and female, between the ages of 18-89 will be enrolled and randomized into either of the following groups; Group 1: These patients will receive a corticosteroid solution with lidocaine containing parabens. Group 2: These patients will receive corticosteroid solution with paraben free lidocaine.

Timeline

Start
2019-09-15
Primary completion
2019-10-15
Completion
2019-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Betamethasone Other / unclassified Other
Subject Triamcinolone Acetonide Other / unclassified Other
Background Lidocaine Other / unclassified 1 %

Indications