drugset / Trial / NCT03574337
Residual Neuromuscular Blockade in Cardiac Surgery Patients
RandomizedParallel-groupQuadruple-blindDiagnostic
Summary
The purpose of this project is to determine if reversal of neuromuscular blockade in cardiac surgery patients expedites time to extubation in fast track patients.
Timeline
- Start
- 2018-08-01
- Primary completion
- 2018-08-30
- Completion
- 2018-08-30
Outcome
Outcome not reported
Stopped (Business): “Inadequate funding”
Publications
- Background Zhu F, Lee A, Chee YE. Fast-track cardiac care for adult cardiac surgical patients. Cochrane Database Syst Rev. 2012 Oct 17;10:CD003587. doi: 10.1002/14651858.CD003587.pub2.
- Results Richey M, Mann A, He J, Daon E, Wirtz K, Dalton A, Flynn BC. Implementation of an Early Extubation Protocol in Cardiac Surgical Patients Decreased Ventilator Time But Not Intensive Care Unit or Hospital Length of Stay. J Cardiothorac Vasc Anesth. 2018 Apr;32(2):739-744. doi: 10.1053/j.jvca.2017.11.007. Epub 2017 Nov 8.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Glycopyrrolate | Small molecule | — | — |
| Comparator | Neostigmine | Other / unclassified | 50 ug/kg | — |
| Comparator | Sugammadex | Other / unclassified | — | — |