TREC-Lebanon: A Trial for Rapid Tranquilisation for Agitated Patients in the Emergency Setting

Phase 4 Completed 100 enrolled Joseph Dib Hopital Psychiatrique De La Croix · collab University of Nottingham · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

This is a randomised controlled trial comparing haloperidol + promethazine versus haloperidol + promethazine + chlorpromazine for agitated patients in the emergency department.

Timeline

Start: 2018-08-28
Primary completion: 2019-07-01
Completion: 2019-07-07

Publications

Dib JE, Adams CE, Ikdais WH, Atallah E, Yaacoub HE, Merheb TJ, Kazour F, Tahan F, Haddad G, Zoghbi M, Azar J, Haddad C, Hallit S. Study protocol for a randomised controlled trial of haloperidol plus promethazine plus chlorpromazine versus haloperidol plus promethazine for rapid tranquilisation for agitated psychiatric patients in the emergency setting (TREC-Lebanon). F1000Res. 2019 Aug 15;8:1442. doi: 10.12688/f1000research.19933.1. eCollection 2019.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Chlorpromazine	Small molecule	—	Intramuscular
Comparator	Haloperidol	Other / unclassified	—	Intramuscular
Comparator	Promethazine	Small molecule	—	Intramuscular

Indications

No indication recorded.