drugset
drugset / Trial / NCT03643822

Adjuncts for Adductor Block: Dexamethasone,Dexmedetomidine, or Combination to Reduce Pain

NCT03643822 ↗

Terminated 3 enrolled Women's College Hospital University Health Network, Toronto · collab
RandomizedParallel-groupDouble-blindOther

Summary

The aim of this multi-centered study is to evaluate the effects of two distinct Adductor Canal Block (ACB) adjuncts, dexamethasone and dexmedetomidine, and their combination, on postoperative analgesia in patients undergoing Anterior Cruciate Ligament (ACL) Repair.

Timeline

Start
2020-02-21
Primary completion
2026-04-16
Completion
2026-04-16

Outcome

Outcome not reported

Stopped: “Since study conception and approval in 2018, we have shown that the analgesic benefit of an adductor canal block is not clinically significant in the setting of ACL reconstruction surgery of the knee.”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 4 mg Other
Comparator Dexmedetomidine Other / unclassified 50 ug Other

Indications

No indication recorded.